ivf blog top banner

IVF and Multiples

It goes without saying that multiple pregnancies are significantly more common following infertility treatment. However, it is clear that the number of embryos in ART pregnancies is entirely controlled by ET (except for MZ splits after sET).

Thus, it is clear that ART (by producing multiple) directly increases prematurity, low birth weight, cerebral palsy, and anomalies. In this sense, it appears that ART fulfils 5 out of the required 6 Wilson's criteria of being a teratogenic procedure

The II Ovarian Club meeting on  ' The fertilization process of the oocyte and embryo development in relation to various clinical conditions', in  Prague , Czech Republic on  November 8-11, 2012 ,is a unique event that will create synergies between basic science, research and daily clinical practice to benefit patient care.More information on:  http://comtecmed.com/oc/2012

The " Ovarian Club" forum aims to help clinicians to reach reliable solutions that can be implemented in their daily practices, and will allow researchers to present their new studies and findings in their fields of expertise creating an inter-active platform for discussions with the leading experts who will attend the Meeting.

Starting fertility treatments can be an exciting yet nerve-raking experience, Dr. IVF's goal is to create an innovative interaction in the doctor-patient relationship and to become part of this important bond.

Dr. IVF, a 3D medical interactive mobile application, creates a new interactive damnation in these relations and gives gynecologists and embryologists the ability to actively illustrate procedures in impressive 3D graphics. Patients will be able to explore, witness and to share with their physician the experience of In Vitro Fertilization. All of those and much more makes the Dr. IVF medical application an important tool in this ultimate one-to-one relationship.

Posted by  Gerald Schatten, an American stem cell researcher
with interests in cell, developmental, and reproductive biology.
Posted on IVF-Worldwide.com on 07 Oct, 2012.

Gerald Schatten (born 1949) is an American stem cell researcher with interests in cell, developmental, and reproductive biology

Notwithstanding the publication last week of our paper generating haploid round spermatid-like cells in vitro from human induced pluripotent stem cells (iPSCs) and embryonic stem cells (ESCs) [Easley et al.,  Direct Differentiation of Human Pluripotent Stem Cells into Haploid Spermatogenic CellsCell Reports 2, 440–446, September 27,  2012], this week another highly significant breakthrough is reported in the jouirnal SCIENCE.

The  in vivoembryo culture device allowing for embryos to be cultured inside the uterine cavity within the intrauterine fluids, effectively enabling crosstalk with the maternal environment. The communication enabled between the maternal environment and the embryos is a fundamental difference between the Anecova method and the other “in-vivo” embryo culture systems using closed vaginal containers filled with artificial medium. 

Various studies using the Anecova method have showed promising results and demonstrated not only the safety and feasibility in a human subject, but also trends of higher implantation potential and higher proportion of euploidy for the embryos cultured  in vivo.A multi-center study is currently underway in Belgium and Denmark on a second-generation device to confirm the trends of higher implantation of  in-vivocultured embryos and gather data on a novel “full  in-vivo” clinical protocol as described below.